Randomized Trialmoderate evidence
Time-Restricted Ketogenic Diet Combined with Exercise Improves Cardiorespiratory Fitness but Compromises Sleep Quality in Overweight and Obese Young Adults: A Randomized Controlled Trial.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme·October 13, 2026·PMID 42868613
Why it mattersKetogenic diets are popular for weight loss and metabolic health, but their effects on sleep—a key factor in recovery and overall health—are poorly understood, especially when combined with exercise. This trial provides direct evidence that short-term KD can transiently impair sleep quality, even as fitness improves, which is relevant for clinicians advising patients on diet and exercise regimens.

The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled