Randomized Trialhigh evidence
Intraoperative methylene blue infusion reduces postoperative delirium in patients undergoing pancreatic surgery: A randomized controlled clinical trial.
Journal of clinical anesthesia·January 1, 2026·PMID 41176956
Why it mattersPostoperative delirium is a common and serious complication in major abdominal surgery, with limited preventive options. This trial provides high-level evidence that a simple, low-cost intraoperative intervention may significantly reduce POD, potentially improving recovery and outcomes.
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