Randomized Trialhigh evidence
Early ultrasound-guided thoracic paravertebral block reduces postherpetic neuralgia and improves functional outcomes in acute herpes zoster: A randomized clinical trial.
Revista espanola de anestesiologia y reanimacion·July 10, 2026·PMID 42431311
Why it mattersAcute herpes zoster carries a high risk of chronic postherpetic neuralgia, which is difficult to treat. This study provides evidence that early regional anesthesia with TPVB can reduce that risk and improve functional outcomes, offering a potential disease-modifying intervention for pain specialists and anesthesiologists managing acute zoster.
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