Randomized Trialhigh evidence

Time-of-day immunochemotherapy in non-small cell lung cancer: a randomized phase 3 trial.

Nature medicine·April 1, 2026·PMID 41629425

Why it matters

Timing of immunotherapy infusion is a low-cost, easily implementable factor that may substantially enhance outcomes in NSCLC. This prospective evidence supports considering time-of-day scheduling to optimize treatment efficacy.

Infographic summary of Time-of-day immunochemotherapy in non-small cell lung cancer: a randomized phase 3 trial.
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