Cohort Studyhigh evidence
A cost-effectiveness analysis of selective decontamination of the digestive tract in mechanically ventilated patients in the intensive care unit.
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine·December 1, 2026·PMID 42751441
Why it mattersICU clinicians and hospital administrators need evidence on whether SDD provides value beyond clinical outcomes. This analysis shows that despite potential reductions in ventilation duration and antibiotic use, SDD does not improve survival and substantially increases costs, making it unlikely to be cost-effective in the Australian setting.

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