Randomized Trialhigh evidence

Earlier Disclosure of Blood-Based Biomarkers, Diagnostic Certainty, and Clinical Management: A Randomized Clinical Trial.

JAMA neurology·October 5, 2026·PMID 42832237

Why it matters

Diagnostic uncertainty in cognitive disorders often delays targeted management and burdens memory clinics with repeated assessments. This trial shows that earlier disclosure of blood-based biomarkers can rapidly increase diagnostic confidence and streamline care, potentially improving patient flow and enabling earlier treatment decisions.

Infographic summary of Earlier Disclosure of Blood-Based Biomarkers, Diagnostic Certainty, and Clinical Management: A Randomized Clinical Trial.
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