Cohort Studymoderate evidence
Multimodal data analysis reveals asynchronous aging dynamics across female reproductive organs.
Nature aging·May 1, 2026·PMID 42056282
Why it mattersFor clinicians caring for midlife women, this study supports menopause as a biologically distinct transition rather than a purely chronological milestone. It also suggests that uterine and vaginal aging may accelerate around menopause and may relate to later pelvic floor and gynecologic health.

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