Randomized Trialhigh evidence
Targeted Use of Computed Tomographic Coronary Angiography in Acute Chest Pain.
The New England journal of medicine·August 29, 2026·PMID 42670980
Why it mattersEmergency physicians and cardiologists often face uncertainty about how to further investigate patients with troponin elevations but no infarction. This trial provides high-quality evidence that routine CT coronary angiography does not reduce subsequent myocardial infarction or cardiac death compared with standard care, informing decisions about post-ED testing strategies.

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