Randomized Trialhigh evidence
Integrating Nonpharmacological Options Into Perioperative Pain Care: A Cluster Randomized Clinical Trial.
JAMA network open·September 1, 2026·PMID 42789267
Why it mattersPostoperative opioid prescribing contributes to opioid-related harms, and scalable strategies to reduce exposure while preserving recovery are needed. This trial shows that an EHR-based intervention can reduce opioid use without worsening patient-reported outcomes, offering a feasible approach for health systems to support safer pain management.

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