Randomized Trialhigh evidence
Quantitative PET coronary flow capacity and comprehensive management of chronic CAD: Lessons from the randomized CENTURY trial.
Atherosclerosis·August 1, 2026·PMID 42435732
Why it mattersFor cardiologists managing chronic CAD, this trial provides randomized evidence that a comprehensive, PET-guided strategy—reserving revascularization for severely reduced CFC—improves hard outcomes over standard care. It reinforces the value of integrating advanced imaging to safely defer revascularization while intensifying prevention.
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