Meta-Analysishigh evidence
Discontinuation of Oral Anticoagulation After Successful Catheter Ablation for Atrial Fibrillation: Meta-Analysis of Randomized Clinical Trials.
Thrombosis and haemostasis·July 15, 2026·PMID 42398953
Why it mattersCurrent guidelines recommend indefinite OAC after ablation regardless of rhythm status, based largely on observational data. This meta-analysis provides randomized evidence that discontinuing OAC after successful ablation may safely reduce bleeding without increasing stroke risk, potentially altering long-term management for many patients.
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