Randomized Trialhigh evidence
Fish oil-derived fatty acids in pregnancy and brain metabolism in middle childhood: results from a randomized controlled trial.
Translational psychiatry·July 16, 2026·PMID 42463642
Why it mattersMaternal PUFA intake is widely promoted for neurodevelopment, yet causal evidence linking supplementation to brain metabolism in children is lacking. This study provides novel, high-level evidence that prenatal PUFA supplementation alters brain metabolic parameters, offering insight into biological mechanisms without immediate cognitive or behavioral correlates.

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