Randomized Trialhigh evidence
Effect of Deep Versus Moderate Neuromuscular Block on Chronic Postsurgical Pain After Lumbar Spine Surgery: A Randomized Clinical Trial.
Anesthesia and analgesia·October 7, 2026·PMID 42848950
Why it mattersChronic postsurgical pain after lumbar fusion is common and difficult to treat. This trial provides evidence that a simple intraoperative adjustment—deep neuromuscular blockade—may reduce early chronic pain and opioid use, potentially by limiting retraction-related muscle injury.
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