Randomized Trialmoderate evidence
Efficacy of Intra-Articular Injection of Platelet-Rich Plasma and Growth Factor Concentrate in Degenerative Meniscal Lesions.
Journal of orthopaedic case reports·October 1, 2026·PMID 42851625
Why it mattersDegenerative meniscal lesions in early knee osteoarthritis cause substantial pain and functional decline, and current treatments are largely palliative. This trial provides head-to-head evidence that GFC may offer superior symptom relief over PRP, while both biologics show structural benefits, informing orthobiologic selection for joint preservation.
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