Randomized Trialhigh evidence
Five-Year Follow-up of a Multicenter Randomized Controlled Trial Comparing an Aragonite-Based Scaffold With Microfracture and Debridement for Chondral and Osteochondral Knee Lesions.
The American journal of sports medicine·May 1, 2026·PMID 41992573
Why it mattersThis study provides long-term evidence that a scaffold-based repair may offer durable clinical improvement over traditional marrow stimulation, even in patients with early osteoarthritis—a group often excluded from cartilage repair trials.
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