Randomized Trialhigh evidence

Effects of Testosterone-Augmented Multimodal Exercise Intervention in Spinal Cord Injury: A Randomized Controlled Trial.

The Journal of clinical endocrinology and metabolism·April 16, 2026·PMID 41988780

Why it matters

Spinal cord injury leads to severe muscle atrophy and metabolic dysfunction that exercise alone only partially addresses. This trial provides evidence that testosterone augmentation can safely enhance lean mass gains and anemia correction in this population, offering a potential strategy to amplify the benefits of rehabilitation.

Infographic summary of Effects of Testosterone-Augmented Multimodal Exercise Intervention in Spinal Cord Injury: A Randomized Controlled Trial.
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