Randomized Trialhigh evidence
Central Obesity and Recurrent Cardiovascular Events in Patients With Obstructive Sleep Apnea: The SAVE Study.
Neurology·August 11, 2026·PMID 42479992
Why it mattersCentral obesity, measured by WHtR, may be a more reliable predictor of recurrent cardiovascular risk than BMI in patients with both OSA and established CVD, challenging reliance on BMI alone for risk stratification in this high-risk population.

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