Randomized Trialhigh evidence
Acetaminophen (Paracetamol) or Opioid Plus Ibuprofen for Children's Musculoskeletal Injury.
JAMA·May 20, 2026·PMID 42160099
Why it mattersPain medicine specialists need evidence to guide pediatric acute pain management while minimizing opioid exposure. This study may inform whether a non-opioid regimen provides comparable analgesia, supporting opioid-sparing approaches in emergency and outpatient settings.
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