Cohort Studyhigh evidence
Human whole-blood NAD+ levels do not vary with age or lifestyle interventions.
Nature metabolism·June 1, 2026·PMID 42135539
Why it mattersMany clinicians and patients track NAD+ as a marker of aging or wellness. This rigorous evidence suggests blood NAD+ is not a useful biomarker for these purposes, which can guide patient counseling and reduce unnecessary testing or supplementation.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled