Randomized Trialhigh evidence
Discomfort of noninvasive ventilation, high flow nasal cannula oxygen, and conventional oxygen implemented after extubation in non-COPD patients.
Critical care (London, England)·May 31, 2026·PMID 42218528
Why it mattersDiscomfort can reduce adherence to post-extubation respiratory support, potentially worsening outcomes. Understanding which modalities are better tolerated helps clinicians select strategies that balance efficacy with patient comfort.

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