Randomized Trialhigh evidence
Tenecteplase Efficacy in Patients With Distal Occlusions: Secondary Analysis of the TASTE Randomized Clinical Trial.
Stroke·July 22, 2026·PMID 42483807
Why it mattersDistal occlusions are common but underrepresented in thrombolytic trials, leaving uncertainty about optimal lytic choice. This analysis suggests tenecteplase may offer superior efficacy over alteplase specifically for very distal MCA occlusions, which could influence agent selection in emergency stroke care.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled