Basic Sciencemoderate evidence
Growth Hormone Receptor Antagonism Extends Lifespan.
Aging cell·September 1, 2026·PMID 42701998
Why it mattersGrowth hormone receptor antagonism is a recognized longevity intervention, yet direct lifespan evidence in rodents was lacking due to poor drug affinity. These findings provide proof-of-concept that GH antagonism improves healthspan and extends lifespan, supporting further development of GH-targeting therapies for aging.
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