Randomized Trialhigh evidence
Effects of legal access versus illegal market cannabis on use and mental health: A randomized controlled trial.
Addiction (Abingdon, England)·October 1, 2025·PMID 40289676
Why it mattersAs jurisdictions consider legal cannabis frameworks, this trial provides early evidence that a public health-oriented model—with regulated products, safer use information, and counseling—may modestly reduce cannabis misuse without worsening mental health, particularly among polysubstance users.
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