Cohort Studyhigh evidence
Risk of perioperative cardiorespiratory complications and mortality associated with preoperative glucagon-like peptide-1 receptor agonist use in type 2 diabetes mellitus: a nationwide propensity-score matched study.
British journal of anaesthesia·January 1, 2026·PMID 40940281
Why it mattersPerioperative management of GLP-1 RAs has been controversial because of aspiration concerns. This large real-world analysis does not support an increased respiratory risk signal in surgical patients with type 2 diabetes and may reassure clinicians when weighing medication holds against glycemic and metabolic stability.
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