Basic Sciencemoderate evidence
Chiral nanoparticles drive enantiomer-specific osteogenic differentiation of stem cells and accelerate bone regeneration.
Science advances·June 12, 2026·PMID 42268950
Why it mattersControlling stem cell fate is a central challenge in regenerative medicine. This work demonstrates that nanoparticle chirality can enantioselectively enhance osteogenesis and angiogenesis, offering a new material-based strategy to improve bone graft substitutes and scaffold design without exogenous growth factors.
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