Randomized Trialhigh evidence
Shared decision making using digital twins in knee osteoarthritis care: a randomized clinical trial of an AI-enabled decision aid versus education alone on decision quality, physical function, and user experience.
EClinicalMedicine·November 1, 2025·PMID 41112505
Why it mattersThis study demonstrates that incorporating personalized benefit–risk predictions via digital twins into shared decision-making can improve decision quality and longer-term functional outcomes in knee OA. It offers a scalable, data-driven approach to augment patient counseling in orthopaedic practice.
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