Comparison of percutaneous 60-day peripheral nerve stimulation of the lumbar medial branches to usual care with standard interventional management for chronic low back pain-a multicenter pragmatic randomized controlled trial (RESET).

Pain medicine (Malden, Mass.)·April 1, 2026·PMID 41138174

Why it matters

This study provides high-level evidence supporting a minimally invasive, temporary neuromodulation option for refractory chronic low back pain, a condition with limited effective treatments. The 60-day PNS approach may offer a meaningful alternative for patients who have not responded to conventional interventional management.