Cohort Studyhigh evidence
Large-scale esophageal cancer screening through noncontrast computed tomography and artificial intelligence.
Nature medicine·September 22, 2026·PMID 42773211
Why it mattersEsophageal cancer is often diagnosed late due to lack of noninvasive screening tools. EAGLE leverages widely available noncontrast CT to identify early malignant and precancerous lesions, potentially enabling opportunistic screening during routine imaging and integration with lung cancer screening programs.
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