Randomized Trialhigh evidence
Magnesium Sulfate to Prevent Perioperative Atrial Fibrillation in Cardiac Surgery: A Randomized Clinical Trial.
Critical care medicine·July 1, 2026·PMID 42206948
Why it mattersProphylactic magnesium is sometimes used empirically to prevent POAF, but this rigorous trial provides strong evidence against its efficacy when targeting high-normal serum levels. It helps clinicians avoid an ineffective intervention that may increase vasopressor use.
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