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Testosterone therapy is associated with reduced risk of acute kidney injury, kidney failure with renal replacement therapy, and cardiovascular events in men with diabetes and hypogonadism.

Cardiovascular diabetology·October 1, 2025·PMID 41035033

Why it matters

Testosterone deficiency is common in diabetic men, yet the renal and cardiovascular effects of testosterone therapy remain unclear. This study provides real-world evidence suggesting potential protective associations, which may inform discussions about testosterone therapy in this high-risk population.

Infographic summary of Testosterone therapy is associated with reduced risk of acute kidney injury, kidney failure with renal replacement therapy, and cardiovascular events in men with diabetes and hypogonadism.
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