Guidelinehigh evidence
Pharmacologic Treatment for Migraine Prevention in Adults Practice Guideline Recommendations: Report of the AAN Guidelines Subcommittee and the American Headache Society.
Headache·August 31, 2026·PMID 42673606
Why it mattersMigraine prevention decisions are often complex, especially in patients with comorbidities or special circumstances. This guideline synthesizes current evidence to help clinicians select appropriate preventive therapies and manage treatment over time, reducing trial-and-error and improving outcomes.

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