Randomized Trialhigh evidence
Histamine is a molecular transducer of adaptation to endurance exercise training in humans.
Journal of applied physiology (Bethesda, Md. : 1985)·June 1, 2025·PMID 40372922
Why it mattersCommon over-the-counter antihistamines may attenuate some training adaptations, which is relevant for pain medicine specialists counseling active patients or those using antihistamines for chronic pain conditions with inflammatory components.
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