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The CBI-M framework for characterization of traumatic brain injury: Evaluation of performance using data from the CENTER-TBI and TRACK-TBI prospective cohort studies.

PLoS medicine·October 1, 2026·PMID 42899481

Why it matters

Acute TBI is highly heterogeneous, and current prognostic models often rely on limited variables. The CBI-M Framework's multimodal approach captures clinically relevant heterogeneity and aligns closely with decision-making and outcomes, potentially improving risk stratification and personalized care in TBI.

Infographic summary of The CBI-M framework for characterization of traumatic brain injury: Evaluation of performance using data from the CENTER-TBI and TRACK-TBI prospective cohort studies.
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