Cohort Studyhigh evidence
The CBI-M framework for characterization of traumatic brain injury: Evaluation of performance using data from the CENTER-TBI and TRACK-TBI prospective cohort studies.
PLoS medicine·October 1, 2026·PMID 42899481
Why it mattersAcute TBI is highly heterogeneous, and current prognostic models often rely on limited variables. The CBI-M Framework's multimodal approach captures clinically relevant heterogeneity and aligns closely with decision-making and outcomes, potentially improving risk stratification and personalized care in TBI.

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