Randomized Trialhigh evidence

Performance of a multi-cancer early detection test in the randomized controlled NHS-Galleri trial.

Nature medicine·September 22, 2026·PMID 42773209

Why it matters

Multi-cancer early detection tests are being considered for population screening, but real-world performance data are limited. These results quantify the test's ability to detect cancers and correctly localize the tissue of origin in a large randomized trial, informing clinicians about expected false-positive rates and missed cancers.

Infographic summary of Performance of a multi-cancer early detection test in the randomized controlled NHS-Galleri trial.
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