Randomized Trialhigh evidence
Effects of a slowly fermentable fiber mixture against the background of a high-protein diet on insulin sensitivity and metabolic health in individuals with overweight: a randomized, placebo-controlled trial.
Gut microbes·December 31, 2026·PMID 41459804
Why it mattersClinicians recommending high-protein diets with fiber supplements for metabolic health should be aware that certain fiber types may paradoxically worsen insulin sensitivity and gut barrier function, challenging the assumption that fiber uniformly improves metabolic outcomes.
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