Cohort Studyhigh evidence
Longitudinal changes in epigenetic clocks predict survival in the InCHIANTI cohort.
Nature aging·March 1, 2026·PMID 41826710
Why it mattersFor clinicians interested in biologic aging and longevity, this study suggests that trajectory of epigenetic age may be more informative than a one-time clock value. It supports these biomarkers as prognostic tools, but not yet as treatment targets or routine clinical tests.
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