Randomized Trialhigh evidence
Revascularization of Asymptomatic Carotid Artery Stenosis: Cognitive Results of the CREST-2 Randomized Trials.
JAMA·September 16, 2026·PMID 42747844
Why it mattersAsymptomatic carotid stenosis is linked to cognitive decline, and revascularization is sometimes considered for cognitive benefit. These robust randomized data clarify that neither stenting nor endarterectomy improves cognition beyond medical management, informing patient counseling and avoiding unnecessary procedures for cognitive indications.

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