Basic Sciencemoderate evidence

Prevalent mesenchymal drift in aging and disease is reversed by partial reprogramming.

Cell·October 16, 2025·PMID 40816266

Why it matters

It provides a mechanistic framework for how partial reprogramming may counteract age-related tissue decline, offering a potential target for interventions in aging and chronic diseases relevant to pain and regenerative medicine.

Infographic summary of Prevalent mesenchymal drift in aging and disease is reversed by partial reprogramming.
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