Randomized Trialhigh evidence
Blood pressure reduction and all-cause dementia in people with uncontrolled hypertension: an open-label, blinded-endpoint, cluster-randomized trial.
Nature medicine·June 1, 2025·PMID 40258956
Why it mattersThis large trial provides strong evidence that aggressive, protocol-driven BP lowering in a real-world, resource-limited setting can reduce dementia risk, addressing a major global health burden. It supports integrating non-physician providers in hypertension management to achieve meaningful cognitive outcomes.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled