Systematic Reviewhigh evidence
Efficacy and Safety of Glucagon-like Peptide-1 Receptor Agonists and Co-agonists for Weight Loss Among Adults Without Diabetes : An Updated Systematic Review.
Annals of internal medicine·September 1, 2026·PMID 42673585
Why it mattersWith an expanding arsenal of GLP-1-based therapies, clinicians need comparative efficacy and safety data to guide selection among available and emerging agents for weight management in patients without diabetes.

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