Randomized Trialhigh evidence

Early Enteral Levothyroxine as Rescue Therapy in Cardiac Surgery Patients With Delayed Neurologic Recovery: A Randomized Trial.

Journal of cardiothoracic and vascular anesthesia·May 11, 2026·PMID 42270554

Why it matters

Delayed neurologic recovery after cardiac surgery is a challenging complication with limited therapeutic options. This trial provides the first randomized evidence that low-dose enteral levothyroxine may accelerate neurologic recovery and improve hemodynamics in this high-risk group, offering a potential low-cost, accessible intervention.

Infographic summary of Early Enteral Levothyroxine as Rescue Therapy in Cardiac Surgery Patients With Delayed Neurologic Recovery: A Randomized Trial.
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