Cohort Studyhigh evidence
Diffusion MRI Identifies a Prolonged Pre-WMH Phase in Cerebral Small Vessel Disease.
Stroke·July 22, 2026·PMID 42483814
Why it mattersCerebral small vessel disease is a major contributor to stroke and dementia, but WMH reflect late-stage injury. Identifying microstructural changes a decade earlier with diffusion MRI could shift clinical focus toward prevention and earlier intervention, potentially before irreversible damage occurs.
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