Randomized Trialhigh evidence

Mobile Units for Integrated Addiction and HIV Prevention Services for People Who Inject Drugs: The HPTN 094 Randomized Clinical Trial.

JAMA psychiatry·November 4, 2026·PMID 42981102

Why it matters

People who inject drugs face high barriers to HIV prevention and opioid use disorder treatment. This trial shows that mobile integrated services did not increase PrEP or MOUD uptake beyond peer navigation, but the mortality reduction suggests potential benefits of enhanced access and engagement.

Infographic summary of Mobile Units for Integrated Addiction and HIV Prevention Services for People Who Inject Drugs: The HPTN 094 Randomized Clinical Trial.
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