Meta-Analysishigh evidence

Impact of propofol-based vs. volatile-based anaesthesia on survival and recurrence after cancer surgery: a systematic review and meta-analysis of randomised trials.

Anaesthesia·August 17, 2026·PMID 42605750

Why it matters

Anesthesiologists have faced conflicting evidence on whether anesthetic technique affects long-term oncologic outcomes. This high-certainty meta-analysis of randomized trials provides robust evidence that propofol-based and volatile-based anesthesia yield equivalent survival and recurrence, allowing clinicians to choose based on other factors without concern for oncologic harm.

Infographic summary of Impact of propofol-based vs. volatile-based anaesthesia on survival and recurrence after cancer surgery: a systematic review and meta-analysis of randomised trials.
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