Randomized Trialhigh evidence
IMpact of PerioperAtive KeTamine on Enhanced Recovery After abdominal Surgery (IMPAKT ERAS): a pragmatic randomised single-cluster trial.
British journal of anaesthesia·December 1, 2025·PMID 40903379
Why it mattersKetamine is widely incorporated into ERAS protocols despite limited evidence. This trial provides robust data that routine ketamine infusion in this setting may be harmful, prompting re-evaluation of its role in multimodal analgesia for abdominal surgery.
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