Randomized Trialhigh evidence
Intraoperative Driving Pressure-Guided High PEEP vs Standard Low PEEP for Postoperative Pulmonary Complications.
JAMA·February 24, 2026·PMID 41334859
Why it mattersIndividualized high PEEP strategies are widely debated for preventing postoperative pulmonary complications. This large, multicenter trial provides high-quality evidence that a driving pressure-guided approach does not reduce pulmonary complications and may increase hemodynamic instability.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled