Randomized Trialhigh evidence
Effect of Dietary Linoleic Acid Intake on Eicosapentaenoic Acid Status and Lipoxygenase-Mediated Oxylipin Biosynthesis in Healthy Adults: A Randomized Controlled Trial.
Nutrients·June 4, 2026·PMID 42280457
Why it mattersHigh dietary linoleic acid, common in Western diets and especially in lower socioeconomic groups, may compromise n-3 fatty acid status and promote a pro-inflammatory oxylipin profile, which has implications for chronic disease risk and nutritional guidance.

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