Randomized Trialhigh evidence
Atherosclerotic cardiovascular disease modifies ambulatory blood pressure response to mandibular advancement device vs. CPAP in obstructive sleep apnoea (ASCVD modifies BP response to OSA therapy).
European journal of preventive cardiology·June 12, 2026·PMID 42284153
Why it mattersThis analysis suggests that in OSA patients with established ASCVD, MAD may offer superior BP reduction compared with CPAP, particularly during sleep. This could influence device selection in a high-risk population where BP control is critical.
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