Cohort Studymoderate evidence
Adiposity, not chronological aging, is the dominant determinant of circulating testosterone in US adult men.
Journal of the Endocrine Society·September 1, 2026·PMID 42661852
Why it mattersTestosterone decline is often attributed to aging, but this study shows adiposity is a far stronger determinant. For clinicians evaluating low testosterone, assessing and addressing obesity—especially central adiposity—may be more relevant than age alone, and simple waist circumference measurement can identify men at risk.
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