Randomized Trialhigh evidence
Liposomal Bupivacaine, Plain Bupivacaine, and Saline for Transversus Abdominis Plane Blocks: The CLEVELAND Randomized Trial.
Anesthesiology·March 1, 2026·PMID 41329063
Why it mattersTAP blocks are widely used in Enhanced Recovery After Surgery pathways, but their efficacy has been debated. This high-quality trial challenges the routine use of single-shot TAP blocks, including those with liposomal bupivacaine, for major abdominal surgery, potentially influencing perioperative pain management protocols.
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